{"schema_version":"secwatch.filing_event.v1","accession":"0000950170-24-123411","form_type":"8-K","ticker":"TECX","cik":"0001681087","company_name":"Tectonic Therapeutic, Inc.","filed_at":"2024-11-07T23:59:59+00:00","discovered_at":"2026-05-14T18:03:09.209285+00:00","generated_at":"2026-05-30T03:38:09.011104+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"neutral","materiality_score":0.7,"calibrated_materiality_score":0.7,"confidence":"high","headline":"Tectonic Therapeutic Q3 net loss $17.7M; TX45 Phase 1b enrollment ahead; new HHT candidate TX2100","bullets":["Net loss of $17.7M for Q3 2024 vs $10.1M a year ago; R&D spend $14.3M (up from $8.1M) on TX45 trials.","Cash $159.1M as of Sept 30, 2024; runway into mid-2027 covering key readouts and HHT program.","Phase 1b hemodynamic trial for TX45 enrollment ahead of plan; topline results expected late Q1 2025/early Q2 2025.","First subject dosed in TX45 APEX Phase 2 trial in Oct 2024; topline data expected 2026.","TX2100 development candidate selected for HHT (no approved therapy); Phase 1 trial expected Q4 2025/Q1 2026."],"urls":{"canonical":"https://secwatch.observer/filing/0000950170-24-123411","json":"https://secwatch.observer/filing/0000950170-24-123411.json","markdown":"https://secwatch.observer/filing/0000950170-24-123411.md","text":"https://secwatch.observer/filing/0000950170-24-123411.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1681087/000095017024123411/0000950170-24-123411-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1681087/000095017024123411/tecx-20241107.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-30T03:38:09.011104+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}