secwatch.observer — SEC 8-K summary ====================================== Issuer: Perspective Therapeutics, Inc. (CATX) CIK: 0000728387 Form: 8-K Filed at: 2024-11-21T23:59:59+00:00 Accession: 0000950170-24-129487 Event type: other_material Sentiment: positive Materiality: 0.75 Item codes: 8.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Perspective Therapeutics reports positive Phase 1/2a data for [212Pb]VMT-α-NET in NETs; pursuing dose escalation -------------------------------------------------------------------------------- - No dose-limiting toxicities observed at 2.5 and 5.0 mCi doses; safety profile favorable. - Eight of nine patients had durable disease control; six of nine had measurable tumor reduction, one confirmed RECIST response. - Safety Monitoring Committee recommends dose escalation to Cohort 3; company to engage with FDA. - Plans to file IND for PSV359 (FAP-α targeting) by end of 2024. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/728387/000095017024129487/0000950170-24-129487-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/728387/000095017024129487/catx-20241121.htm HTML page: https://secwatch.observer/filing/0000950170-24-129487 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer