other material
confidence high
sentiment neutral
materiality 0.65
MindMed doses first patient in Phase 3 Voyage study of MM120 for GAD
Definium Therapeutics, Inc.
- First-ever Phase 3 study of lysergide D-tartrate (LSD) for GAD; primary endpoint HAM-A change at week 12 vs placebo.
- Voyage study to enroll ~200 participants in US; topline data from 12-week double-blind period expected H1 2026.
- Builds on positive Phase 2b study results presented at APA Annual Meeting in May 2024; second Phase 3 Panorama study on track for H1 2025.
- MM120 ODT is a pharmaceutically optimized form of LSD; study includes 52-week duration with 40-week open-label extension.