secwatch.observer — SEC 8-K summary ====================================== Issuer: Trevi Therapeutics, Inc. (TRVI) CIK: 0001563880 Form: 8-K Filed at: 2025-01-08T23:59:59+00:00 Accession: 0000950170-25-003286 Event type: other_material Sentiment: neutral Materiality: 0.60 Item codes: 2.02, 8.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Trevi Therapeutics reports $107.6M cash; Phase 2a RIVER completed enrollment; CORAL 80% enrolled -------------------------------------------------------------------------------- - Cash, cash equivalents, and marketable securities estimated at $107.6M as of Dec 31, 2024; runway into H2 2026. - Last patient completed final visit in Phase 2a RIVER trial (RCC); topline results expected Q1 2025. - Phase 2b CORAL trial (IPF chronic cough) now ~80% enrolled after positive SSRE; topline expected H1 2025. - SSRE analysis in Dec 2024 reaffirmed original sample size of N=160 for CORAL trial. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1563880/000095017025003286/0000950170-25-003286-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1563880/000095017025003286/trvi-20250108.htm HTML page: https://secwatch.observer/filing/0000950170-25-003286 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer