secwatch.observer — SEC 8-K summary ====================================== Issuer: Perspective Therapeutics, Inc. (CATX) CIK: 0000728387 Form: 8-K Filed at: 2025-01-24T23:59:59+00:00 Accession: 0000950170-25-008603 Event type: other_material Sentiment: positive Materiality: 0.75 Item codes: 8.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Perspective Therapeutics reports updated Phase 1/2a data for [212Pb]VMT-α-NET: 3 objective responses, no DLTs -------------------------------------------------------------------------------- - Three objective responses (1 confirmed, 2 unconfirmed) in Cohort 2 at 5.0 mCi dose; 5 stable disease; 1 progressive disease. - No dose-limiting toxicities, grade 4/5 events, or SAEs reported; hematologic AEs were grade 1-2 only. - Additional 11 patients dosed in Cohort 2 since August 2024, totaling 18 as of Dec 31, 2024. - Company pursuing dose escalation to Cohort 3 after FDA consultation; data submitted to FDA in December 2024. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/728387/000095017025008603/0000950170-25-008603-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/728387/000095017025008603/catx-20250124.htm HTML page: https://secwatch.observer/filing/0000950170-25-008603 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer