{"schema_version":"secwatch.filing_event.v1","accession":"0000950170-25-009474","form_type":"8-K","ticker":"SABS","cik":"0001833214","company_name":"SAB Biotherapeutics, Inc.","filed_at":"2025-01-28T23:59:59+00:00","discovered_at":"2026-05-14T18:03:05.163520+00:00","generated_at":"2026-05-27T08:27:09.281680+00:00","sec_items":["8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.7,"calibrated_materiality_score":0.7,"confidence":"high","headline":"SAB Biotherapeutics reports positive Phase 1 topline results for T1D therapy SAB-142; plans Phase 2b in 2025","bullets":["Phase 1 trial of SAB-142 met primary safety and PD objectives; generally well-tolerated, no serum sickness or anti-drug antibodies at target dose.","SAB-142 showed sustained immunomodulation with MoA analogous to rabbit ATG, correlative to C-peptide preservation.","Company plans to advance SAB-142 into Phase 2b trial in 2025 for adult and pediatric patients with new-onset T1D.","Results presented at R&D webinar on Jan 28, 2025; KOL Michael Haller, MD from Univ of Florida participated."],"urls":{"canonical":"https://secwatch.observer/filing/0000950170-25-009474","json":"https://secwatch.observer/filing/0000950170-25-009474.json","markdown":"https://secwatch.observer/filing/0000950170-25-009474.md","text":"https://secwatch.observer/filing/0000950170-25-009474.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1833214/000095017025009474/0000950170-25-009474-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1833214/000095017025009474/sabs-20250128.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-27T08:27:09.281680+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}