{"schema_version":"secwatch.filing_event.v1","accession":"0000950170-25-024134","form_type":"8-K","ticker":"ASMB","cik":"0001426800","company_name":"ASSEMBLY BIOSCIENCES, INC.","filed_at":"2025-02-20T23:59:59+00:00","discovered_at":"2026-05-14T18:03:03.601647+00:00","generated_at":"2026-05-26T08:27:57.846423+00:00","sec_items":["8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.8,"calibrated_materiality_score":0.8,"confidence":"high","headline":"Assembly Biosciences reports positive interim Phase 1a results for ABI-1179 in recurrent genital herpes","bullets":["ABI-1179 had a half-life of ~4 days and high exposure across 50mg-300mg doses, supporting once-weekly oral dosing.","ABI-1179 was well-tolerated with no serious adverse events and all treatment-emergent AEs mild and unrelated.","Company plans to move directly into Phase 1b, running concurrently with Phase 1b of ABI-5366.","Interim Phase 1b data for both ABI-1179 and ABI-5366 anticipated in fall 2025.","ABI-1179 contributed by Gilead Sciences under the Assembly Bio-Gilead collaboration."],"urls":{"canonical":"https://secwatch.observer/filing/0000950170-25-024134","json":"https://secwatch.observer/filing/0000950170-25-024134.json","markdown":"https://secwatch.observer/filing/0000950170-25-024134.md","text":"https://secwatch.observer/filing/0000950170-25-024134.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1426800/000095017025024134/0000950170-25-024134-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1426800/000095017025024134/asmb-20250220.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud","generated_at":"2026-05-26T08:27:57.846423+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}