secwatch.observer — SEC 8-K summary
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Issuer:     PepGen Inc. (PEPG)
CIK:        0001835597
Form:       8-K
Filed at:   2025-03-04T23:59:59+00:00
Accession:  0000950170-25-031337
Event type: other_material
Sentiment:  negative
Materiality: 0.75
Item codes: 8.01, 9.01
LLM model:  deepseek-v4-flash:cloud@v2

PepGen voluntarily pauses Phase 2 CONNECT2-EDO51 study; awaits 10 mg/kg data from CONNECT1
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- Temporarily pauses CONNECT2-EDO51 in DMD until review of 10 mg/kg data from ongoing CONNECT1-EDO51 study.
- No new safety issues observed in PGN-EDO51 program since safety update on January 23, 2025.
- CONNECT1 10 mg/kg cohort fully enrolled; data expected in third quarter of 2025.
- Resources focused on completing CONNECT1 and advancing FREEDOM-DM1 studies in myotonic dystrophy type 1.
- CEO states pause allows gathering additional safety data and potential improvement of CONNECT2 design.

Source:
  EDGAR index:    https://www.sec.gov/Archives/edgar/data/1835597/000095017025031337/0000950170-25-031337-index.htm
  Primary doc:    https://www.sec.gov/Archives/edgar/data/1835597/000095017025031337/pepg-20250304.htm
  HTML page:      https://secwatch.observer/filing/0000950170-25-031337

License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer