secwatch.observer — SEC 8-K summary ====================================== Issuer: Inozyme Pharma, Inc. (—) CIK: 0001693011 Form: 8-K Filed at: 2025-03-10T23:59:59+00:00 Accession: 0000950170-25-035939 Event type: earnings Sentiment: negative Materiality: 0.75 Item codes: 2.02, 2.05, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Inozyme reports FY2024 net loss of $102M; cuts 25% workforce to focus on ENPP1 Deficiency -------------------------------------------------------------------------------- - FY2024 net loss $102.0M ($1.62 per share) vs $71.2M ($1.37 per share) in 2023. - Cash, equivalents & ST investments $113.1M; expects runway into Q1 2026 after prioritization. - Workforce reduction of ~25%; $1.8M expected charges, substantially complete by Q3 2025. - Completed enrollment in ENERGY 3 trial (N=27) for INZ-701; topline data expected Q1 2026. - ABCC6 Deficiency and calciphylaxis trials postponed; only ongoing treatment for existing patients continues. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1693011/000095017025035939/0000950170-25-035939-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1693011/000095017025035939/inzy-20250307.htm HTML page: https://secwatch.observer/filing/0000950170-25-035939 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer