secwatch.observer — SEC 8-K summary ====================================== Issuer: Lyra Therapeutics, Inc. (LYRA) CIK: 0001327273 Form: 8-K Filed at: 2025-03-13T23:59:59+00:00 Accession: 0000950170-25-038742 Event type: other_material Sentiment: neutral Materiality: 0.65 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Lyra Therapeutics reports FY2024 net loss $93.4M; ENLIGHTEN 2 top-line data expected Q2 2025 -------------------------------------------------------------------------------- - Net loss for FY2024 was $93.4M ($1.43 diluted EPS) vs $62.7M in FY2023; cash $40.6M as of Dec 31, 2024. - Top-line results from ENLIGHTEN 2 Phase 3 trial of LYR-210 in CRS expected in Q2 2025. - Positive post-hoc data from ENLIGHTEN 1 extension in polyp cohort; FDA alignment on registration path for CRSwNP. - Planned reverse stock split to maintain Nasdaq listing; requires shareholder approval in Q2 2025. - R&D expenses decreased to $43.8M from $48.0M due to trial completions and workforce reduction. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1327273/000095017025038742/0000950170-25-038742-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1327273/000095017025038742/lyra-20250313.htm HTML page: https://secwatch.observer/filing/0000950170-25-038742 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer