---
schema_version: "secwatch.filing_event.v1"
accession: "0000950170-25-046756"
form_type: "8-K"
ticker: "ALEC"
cik: "0001653087"
company_name: "Alector, Inc."
filed_at: "2025-03-28T23:59:59+00:00"
generated_at: "2026-05-24T03:08:13.952152+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.55
calibrated_materiality_score: 0.55
confidence: "high"
source: SEC EDGAR
---

# Alector CMO Gary Romano resigns effective April 25, 2025

## Summary
- Dr. Gary Romano notified resignation from CMO role on March 25, 2025.
- Resignation effective April 25, 2025; he leaves to pursue other opportunities.
- Romano served as CMO since May 2022; no successor announced yet.

## SEC filing metadata
- accession: 0000950170-25-046756
- form_type: 8-K
- ticker: ALEC
- cik: 0001653087
- company_name: Alector, Inc.
- filed_at: 2025-03-28T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.55
- calibrated_materiality_score: 0.55
- confidence: high
- sec_items: 5.02
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1653087/000095017025046756/0000950170-25-046756-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1653087/000095017025046756/alec-20250325.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0000950170-25-046756
- JSON: https://secwatch.observer/filing/0000950170-25-046756.json
- Plain text: https://secwatch.observer/filing/0000950170-25-046756.txt

## Key facts
- Executive change
  Gary Romano resigned as Chief Medical Officer at Alector, Inc..
  - Action: resigned
  - Role: Chief Medical Officer
  source text: On March 25, 2025, Dr. Gary Romano gave notice of his decision to resign from his position as Chief Medical Officer of Alector, Inc. (the “Company”) in order to pursue other opportunities.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1653087/000095017025046756/0000950170-25-046756-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.