{"schema_version":"secwatch.filing_event.v1","accession":"0000950170-25-047207","form_type":"8-K","ticker":"MAZE","cik":"0001842295","company_name":"Maze Therapeutics, Inc.","filed_at":"2025-03-31T23:59:59+00:00","discovered_at":"2026-05-14T18:03:05.232896+00:00","generated_at":"2026-05-24T02:23:18.352022+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"positive","materiality_score":0.7,"calibrated_materiality_score":0.7,"confidence":"high","headline":"Maze Therapeutics: Q4 net loss $29.6M, FY net income $52.2M on $167.5M license revenue; cash runway into H2 2027","bullets":["Q4 net loss $29.6M vs $26.6M loss a year ago; FY net income $52.2M vs $100.4M loss in 2023.","Cash and cash equivalents $196.8M as of Dec 31, 2024, up from $29.2M; combined with Feb 2025 IPO proceeds of $140M provides runway into H2 2027.","License revenue of $167.5M in FY2024 primarily from $150M upfront from Shionogi for MZE001.","Phase 2 HORIZON trial of MZE829 for AKD dosing patients; initial data expected Q1 2026.","Phase 1 trial of MZE782 ongoing; initial data including proof-of-mechanism expected H2 2025."],"urls":{"canonical":"https://secwatch.observer/filing/0000950170-25-047207","json":"https://secwatch.observer/filing/0000950170-25-047207.json","markdown":"https://secwatch.observer/filing/0000950170-25-047207.md","text":"https://secwatch.observer/filing/0000950170-25-047207.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1842295/000095017025047207/0000950170-25-047207-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1842295/000095017025047207/maze-8k-q424_earnings.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-24T02:23:18.352022+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}