---
schema_version: "secwatch.filing_event.v1"
accession: "0000950170-25-057685"
form_type: "8-K"
ticker: "VIVS"
cik: "0001497253"
company_name: "VivoSim Labs, INC."
filed_at: "2025-04-24T23:59:59+00:00"
generated_at: "2026-05-23T06:57:53.636476+00:00"
event_type: "other_material"
sentiment: "positive"
materiality_score: 0.7
calibrated_materiality_score: 0.7
confidence: "high"
source: SEC EDGAR
---

# Organovo Holdings renames to VivoSim Labs, emerges from stealth to target FDA animal testing phase-out

## Summary
- Effective April 24, 2025, Organovo Holdings changed its name to VivoSim Labs, Inc. with new ticker symbol VIVS on Nasdaq.
- In conjunction with the name change, VivoSim issued a press release announcing emergence from stealth mode to provide NAM models for liver and intestinal toxicology.
- The FDA announced on April 10, 2025 a plan to phase out animal testing requirements, representing a potential >$10B market opportunity for VivoSim's non-animal technologies.
- VivoSim’s NAMkind liver model achieved industry-best correlation with known clinical failures, aiming to reduce clinical trial failures and cut drug development costs by 50%.
- The company's NAMkind intestine models offer novel readouts for drug candidate selection, targeting reduction of patient side effects from chemotherapy.

## SEC filing metadata
- accession: 0000950170-25-057685
- form_type: 8-K
- ticker: VIVS
- cik: 0001497253
- company_name: VivoSim Labs, INC.
- filed_at: 2025-04-24T23:59:59+00:00
- event_type: other_material
- sentiment: positive
- materiality_score: 0.7
- calibrated_materiality_score: 0.7
- confidence: high
- sec_items: 5.03, 7.01, 8.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1497253/000095017025057685/0000950170-25-057685-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1497253/000095017025057685/vivs-20250423.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0000950170-25-057685
- JSON: https://secwatch.observer/filing/0000950170-25-057685.json
- Plain text: https://secwatch.observer/filing/0000950170-25-057685.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.