other material
confidence high
sentiment positive
materiality 0.50
Perspective Therapeutics doses first patient in Phase 1/2a trial of PSV359 for FAP-α positive solid tumors
Perspective Therapeutics, Inc.
- First patient dosed with [212Pb]PSV359 in Phase 1/2a dose-finding trial for FAP-α positive solid tumors.
- Patients selected via SPECT imaging with [203Pb]PSV359 to identify FAP-α expression.
- Trial aims to determine safety and preliminary anti-tumor activity; dose selection for monotherapy or combination.
- PSV359 construct optimized for tumor uptake, retention, and fast clearance from healthy tissues.