secwatch.observer — SEC 8-K summary ====================================== Issuer: Lyra Therapeutics, Inc. (LYRA) CIK: 0001327273 Form: 8-K Filed at: 2025-05-06T23:59:59+00:00 Accession: 0000950170-25-064475 Event type: earnings Sentiment: negative Materiality: 0.70 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Lyra Therapeutics reports Q1 net loss of $8.5M; ENLIGHTEN 2 top-line results expected Q2 2025 -------------------------------------------------------------------------------- - Net loss of $8.5M ($0.13 per share) vs. $22.5M ($0.35) in Q1 2024; cash burn reduced YoY. - Cash & equivalents $31.7M at March 31, 2025, down from $40.6M at Dec 31, 2024. - Topline Phase 3 ENLIGHTEN 2 data for LYR-210 in CRS expected in Q2 2025; ~65 polyp patients across both ENLIGHTEN trials. - Plans a reverse stock split to comply with Nasdaq $1.00 minimum bid; stockholder vote on May 14, 2025. - R&D expenses fell to $4.9M from $18.2M YoY, driven by completion of BEACON and ENLIGHTEN 1 trials and May 2024 workforce reduction. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1327273/000095017025064475/0000950170-25-064475-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1327273/000095017025064475/lyra-20250506.htm HTML page: https://secwatch.observer/filing/0000950170-25-064475 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer