{"schema_version":"secwatch.filing_event.v1","accession":"0000950170-25-070305","form_type":"8-K","ticker":"ANTX","cik":"0001880438","company_name":"AN2 Therapeutics, Inc.","filed_at":"2025-05-13T23:59:59+00:00","discovered_at":"2026-05-14T18:02:50.357346+00:00","generated_at":"2026-05-21T18:37:17.760304+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"neutral","materiality_score":0.6,"calibrated_materiality_score":0.6,"confidence":"high","headline":"AN2 Therapeutics reports Q1 2025 net loss of $10.6M; cash runway extended to 2028","bullets":["Net loss of $10.6M vs $16.6M in Q1 2024; R&D expenses down to $7.7M from $14.7M.","Cash and investments of $78.5M at March 31, 2025; operating runway now projected into 2028.","Initiated Phase 1 first-in-human study of AN2-502998 for chronic Chagas disease; expected completion in H2 2025.","Plans to initiate Phase 2 study of epetraborole in melioidosis; advancing epetraborole for NTM lung disease non-dilutive.","Oncology pipeline advancing; first compound(s) expected to enter development in 2025 within current cash runway."],"urls":{"canonical":"https://secwatch.observer/filing/0000950170-25-070305","json":"https://secwatch.observer/filing/0000950170-25-070305.json","markdown":"https://secwatch.observer/filing/0000950170-25-070305.md","text":"https://secwatch.observer/filing/0000950170-25-070305.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1880438/000095017025070305/0000950170-25-070305-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1880438/000095017025070305/antx-20250513.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-21T18:37:17.760304+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}