secwatch.observer — SEC 8-K summary ====================================== Issuer: Rapport Therapeutics, Inc. (RAPP) CIK: 0002012593 Form: 8-K Filed at: 2025-06-02T23:59:59+00:00 Accession: 0000950170-25-080247 Event type: other_material Sentiment: positive Materiality: 0.70 Item codes: 7.01, 8.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 RAP-219 Phase 2a fully enrolled; topline data Sept 2025; safety profile clean ----------------------------------------------------------------------------- - Phase 2a trial of RAP-219 in refractory focal epilepsy fully enrolled; topline results expected September 2025. - Consolidated Phase 1 safety data (n=64) shows all TEAEs Grade 1/2, no SAEs; common: headache, dry mouth, brain fog, fatigue. - Upcoming catalysts: initiate Phase 2a in bipolar mania Q3 2025, update on diabetic neuropathic pain program 2H 2025. - Cash, cash equivalents and short-term investments of $285.4M as of March 31, 2025; runway through end of 2026. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/2012593/000095017025080247/0000950170-25-080247-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/2012593/000095017025080247/rapp-20250602.htm HTML page: https://secwatch.observer/filing/0000950170-25-080247 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer