secwatch.observer — SEC 8-K summary ====================================== Issuer: Alector, Inc. (ALEC) CIK: 0001653087 Form: 8-K Filed at: 2025-08-07T23:59:59+00:00 Accession: 0000950170-25-105023 Event type: earnings Sentiment: neutral Materiality: 0.65 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Alector Q2 net loss $30.5M; cash $307.3M; Phase 3 latozinemab data mid-Q4 ------------------------------------------------------------------------- - Net loss $30.5M ($0.30/sh) vs $38.7M ($0.40/sh) in Q2 2024; revenue $7.9M down from $15.1M. - Cash, cash equivalents, and investments $307.3M, providing runway into H2 2027. - On track to report topline data from INFRONT-3 Phase 3 trial of latozinemab in FTD-GRN by mid-Q4 2025. - Guidance updated: collaboration revenue $13-18M, R&D expenses $130-140M, G&A $55-65M for FY2025. - Neil Berkley appointed interim CFO; USPTO issued patent for latozinemab treatment method. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1653087/000095017025105023/0000950170-25-105023-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1653087/000095017025105023/alec-20250807.htm HTML page: https://secwatch.observer/filing/0000950170-25-105023 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer