earnings
confidence high
sentiment neutral
materiality 0.60
Prelude Therapeutics Q2 net loss $31.2M; pauses IV SMARCA2 degrader, focuses on oral PRT7732
Prelude Therapeutics Inc
2025-Q2 EPS
reported -$0.83
vs consensus -$0.45
▼ miss
(-85.1%)
- Net loss of $31.2M ($0.41 per share) improved from $34.7M ($0.46) in Q2 2024.
- Cash, equivalents and marketable securities $77.3M; runway into Q2 2026.
- PRT3789 (IV) Phase 1 completed; will only advance with partnership. Oral PRT7732 enrolling 7th cohort (125 mg once daily); initial data by year-end 2025.
- KAT6A degrader development candidate selected; IND on track for H1 2026.
- R&D expense $25.8M (down from $29.5M); G&A $6.4M (down from $7.7M) YoY.
item 2.02item 7.01item 9.01