secwatch.observer — SEC 8-K summary ====================================== Issuer: Tyra Biosciences, Inc. (TYRA) CIK: 0001863127 Form: 8-K Filed at: 2025-08-14T23:59:59+00:00 Accession: 0000950170-25-108876 Event type: earnings Sentiment: neutral Materiality: 0.55 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Tyra Biosciences Q2 2025 cash $296.3M; dosed first patient in SURF302 NMIBC trial -------------------------------------------------------------------------------- - Cash, cash equivalents and marketable securities of $296.3M as of June 30, 2025; runway through at least 2027. - Q2 net loss of $28.1M, vs $18.7M in Q2 2024; R&D expenses $24.3M (up from $18.0M). - Dosed first patient in SURF302 Phase 2 study of dabogratinib for FGFR3-altered intermediate-risk NMIBC. - BEACH301 Phase 2 achondroplasia study now enrolling safety sentinel cohort; dose first child expected 3Q 2025. - Initial three-month complete response data from SURF302 expected in first half 2026. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1863127/000095017025108876/0000950170-25-108876-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1863127/000095017025108876/tyra-20250814.htm HTML page: https://secwatch.observer/filing/0000950170-25-108876 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer