secwatch.observer — SEC 8-K summary ====================================== Issuer: SANGAMO THERAPEUTICS, INC (SGMO) CIK: 0001001233 Form: 8-K Filed at: 2025-11-06T23:59:59+00:00 Accession: 0001001233-25-000023 Event type: earnings Sentiment: negative Materiality: 0.75 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Sangamo Q3 net loss $34.9M, revenue $0.6M; advancing Fabry BLA and pain trial enrollment -------------------------------------------------------------------------------- - Q3 2025 consolidated net loss $34.9M ($0.11/sh) vs net income $10.7M ($0.04/sh) in prior year. - Revenue of $0.6M down from $49.4M, mainly due to absence of Genentech collaboration revenue. - Cash and equivalents $29.6M; with Pfizer $6M license fee and ATM proceeds, runway into Q1 2026. - FDA reiterated eGFR slope endpoint for isaralgagene civaparvovec accelerated approval; BLA submission expected as early as Q1 2026. - First two clinical sites activated for Phase 1/2 ST-503 chronic neuropathic pain study; first patient dosing expected in coming months. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1001233/000100123325000023/0001001233-25-000023-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1001233/000100123325000023/sgmo-20251106.htm HTML page: https://secwatch.observer/filing/0001001233-25-000023 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer