---
schema_version: "secwatch.filing_event.v1"
accession: "0001062822-21-000046"
form_type: "8-K"
ticker: "LXRX"
cik: "0001062822"
company_name: "LEXICON PHARMACEUTICALS, INC."
filed_at: "2021-08-02T23:59:59+00:00"
generated_at: "2026-06-29T23:45:08.277153+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.45
calibrated_materiality_score: 0.45
confidence: "high"
source: SEC EDGAR
---

# Lexicon Pharmaceuticals announces principal accounting officer retirement and CMO appointment

## Summary
- James F. Tessmer to retire as VP of finance and accounting (principal accounting officer) effective Sept 24, 2021.
- Kristen L. Alexander, current controller, to succeed Tessmer as VP of finance and accounting and principal accounting officer on Sept 24, 2021.
- Craig B. Granowitz, M.D., Ph.D., appointed Senior VP and Chief Medical Officer effective Aug 2, 2021; previously CMO of Amarin.
- Dr. Granowitz brings prior experience from Merck & Co., Inc. and Schering-Plough Corporation.

## SEC filing metadata
- accession: 0001062822-21-000046
- form_type: 8-K
- ticker: LXRX
- cik: 0001062822
- company_name: LEXICON PHARMACEUTICALS, INC.
- filed_at: 2021-08-02T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.45
- calibrated_materiality_score: 0.45
- confidence: high
- sec_items: 5.02, 8.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1062822/000106282221000046/0001062822-21-000046-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1062822/000106282221000046/lxrx-20210728.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001062822-21-000046
- JSON: https://secwatch.observer/filing/0001062822-21-000046.json
- Plain text: https://secwatch.observer/filing/0001062822-21-000046.txt

## Key facts
- Executive change
  James F. Tessmer retired as vice president of finance and accounting at LEXICON PHARMACEUTICALS, INC..
  - Action: retired
  - Role: vice president of finance and accounting
  source text: On July 28, 2021, James F. Tessmer notified us of his decision to retire as our vice president of finance and accounting, effective September 24, 2021.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1062822/000106282221000046/0001062822-21-000046-index.htm
- Executive change
  Kristen L. Alexander was appointed as vice president of finance and accounting at LEXICON PHARMACEUTICALS, INC..
  - Action: appointed
  - Role: vice president of finance and accounting
  source text: Effective September 24, 2021, Kristen L. Alexander will become our vice president of finance and accounting and assume the function of our principal accounting officer.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1062822/000106282221000046/0001062822-21-000046-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.