Lexicon amends loan with Oxford Finance; $25M tranche drawable Dec 1-31, 2022

LEXICON PHARMACEUTICALS, INC.

First Amendment to Loan and Security Agreement with Oxford Finance LLC executed Aug 29, 2022.
Second $25M tranche draw period changed to Dec 1-31, 2022, subject to conditions and no Event of Default.
Sotagliflozin NDA Milestone already achieved, as confirmed by Collateral Agent.
Amendment fee and Lender Expenses payable; other loan terms unchanged.

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