---
schema_version: "secwatch.filing_event.v1"
accession: "0001062822-26-000098"
form_type: "8-K"
ticker: "LXRX"
cik: "0001062822"
company_name: "LEXICON PHARMACEUTICALS, INC."
filed_at: "2026-05-07T23:59:59+00:00"
generated_at: "2026-05-14T21:22:25.146146+00:00"
event_type: "earnings"
sentiment: "positive"
materiality_score: 0.65
calibrated_materiality_score: 0.65
confidence: "high"
source: SEC EDGAR
---

# Lexicon Q1 net loss narrows to $1M on $21.1M revenue; pipeline on track

## Summary
- Total revenues $21.1M (vs $1.3M), including $20M Novo Nordisk milestone; net loss $1.0M (vs $25.3M).
- Cash and investments $199.7M at March 31, 2026; $96.5M stock sale; $100M Hercules loan facility (initial $55M funded).
- SONATA-HCM enrollment completion mid-2026; topline results expected Q1 2027.
- ZYNQUISTA NDA resubmission for T1D mid-2026; potential approval in 2026.
- LX9851 Phase 1 started by Novo Nordisk; $10M milestone earned; up to $1B in total milestones.

## SEC filing metadata
- accession: 0001062822-26-000098
- form_type: 8-K
- ticker: LXRX
- cik: 0001062822
- company_name: LEXICON PHARMACEUTICALS, INC.
- filed_at: 2026-05-07T23:59:59+00:00
- event_type: earnings
- sentiment: positive
- materiality_score: 0.65
- calibrated_materiality_score: 0.65
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1062822/000106282226000098/0001062822-26-000098-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1062822/000106282226000098/lxrx-20260507.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001062822-26-000098
- JSON: https://secwatch.observer/filing/0001062822-26-000098.json
- Plain text: https://secwatch.observer/filing/0001062822-26-000098.txt

## Source-grounded claims
- claim_id: 149cba53fe453dda6a81a068a08eb29062ea7826
  claim: LEXICON PHARMACEUTICALS, INC. reported quarter ended March 31, 2026 results: revenue $21.1 million.
  evidence_excerpt: Total revenues were $21.1 million for the first quarter of 2026
  evidence_url: https://www.sec.gov/Archives/edgar/data/1062822/000106282226000098/0001062822-26-000098-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.