---
schema_version: "secwatch.filing_event.v1"
accession: "0001079973-25-001778"
form_type: "8-K"
ticker: "PKTX"
cik: "0001128189"
company_name: "ProtoKinetix, Inc."
filed_at: "2025-11-17T23:59:59+00:00"
generated_at: "2026-05-16T19:06:21.829062+00:00"
event_type: "leadership"
sentiment: "negative"
materiality_score: 0.8
calibrated_materiality_score: 0.8
confidence: "high"
source: SEC EDGAR
---

# ProtoKinetix CEO Clarence Smith dies in accident; CFO Guzzetta assumes all top roles

## Summary
- CEO Clarence E. Smith died Nov 13, 2025 in a tragic accident; served as CEO since 2015.
- Sole remaining director Ed McDonough appointed Michael Guzzetta as Chairman, CEO, President on Nov 16.
- Guzzetta continues as CFO, Secretary, Treasurer; his 2017 employment agreement unchanged.
- ProtoKinetix is a clinical-stage biomedical company (OTC: PKTX) with no disclosed financial impact.

## SEC filing metadata
- accession: 0001079973-25-001778
- form_type: 8-K
- ticker: PKTX
- cik: 0001128189
- company_name: ProtoKinetix, Inc.
- filed_at: 2025-11-17T23:59:59+00:00
- event_type: leadership
- sentiment: negative
- materiality_score: 0.8
- calibrated_materiality_score: 0.8
- confidence: high
- sec_items: 5.02, 7.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1128189/000107997325001778/0001079973-25-001778-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1128189/000107997325001778/pktx_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001079973-25-001778
- JSON: https://secwatch.observer/filing/0001079973-25-001778.json
- Plain text: https://secwatch.observer/filing/0001079973-25-001778.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.