secwatch.observer — SEC 8-K summary ====================================== Issuer: RHYTHM PHARMACEUTICALS, INC. (RYTM) CIK: 0001649904 Form: 8-K Filed at: 2021-09-02T23:59:59+00:00 Accession: 0001104659-21-112483 Event type: leadership Sentiment: neutral Materiality: 0.70 Item codes: 5.02, 7.01 LLM model: deepseek-v4-flash:cloud@v2 Rhythm Pharma CMO resigns; new CMO appointed; updated Phase 3 data on setmelanotide -------------------------------------------------------------------------------- - Dr. Murray Stewart resigns as CMO effective Sept 10, 2021; will serve as Senior Medical Advisor for up to one year at $12,000/month. - Linda Shapiro Manning, M.D., Ph.D., appointed as new CMO effective Sept 10; previously SVP Clinical. - Updated slide presentation includes new BMI reduction data from Phase 3 Bardet-Biedl syndrome trial and EMANATE powering assumptions. - Stewart's vested options remain exercisable 3 months post-consulting; unvested options forfeited; RSUs continue vesting. - Stewart eligible for prorated 2021 annual bonus based on employment and part-time consulting. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1649904/000110465921112483/0001104659-21-112483-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1649904/000110465921112483/tm2126899d1_8k.htm HTML page: https://secwatch.observer/filing/0001104659-21-112483 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer