---
schema_version: "secwatch.filing_event.v1"
accession: "0001104659-22-114206"
form_type: "8-K"
ticker: "TVRD"
cik: "0001346830"
company_name: "Tvardi Therapeutics, Inc."
filed_at: "2022-11-03T23:59:59+00:00"
generated_at: "2026-06-22T08:24:50.748963+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.3
calibrated_materiality_score: 0.3
confidence: "high"
source: SEC EDGAR
---

# Cara Therapeutics appoints Lisa von Moltke, M.D. to Board of Directors

## Summary
- Dr. von Moltke is EVP and Chief Medical Officer at Seres Therapeutics, with prior roles at Alkermes and Sanofi.
- She will receive $45K annual cash retainer, $5K for nominating committee, and initial option grant of $350K vesting quarterly over 3 years.
- Appointment effective November 1, 2022; term expires at 2023 Annual Meeting; she will serve on nominating and corporate governance committee.
- Her expertise is expected to support execution of strategy for oral difelikefalin in pruritus, a key pipeline program.

## SEC filing metadata
- accession: 0001104659-22-114206
- form_type: 8-K
- ticker: TVRD
- cik: 0001346830
- company_name: Tvardi Therapeutics, Inc.
- filed_at: 2022-11-03T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.3
- calibrated_materiality_score: 0.3
- confidence: high
- sec_items: 5.02, 7.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1346830/000110465922114206/0001104659-22-114206-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1346830/000110465922114206/tm2229601d1_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001104659-22-114206
- JSON: https://secwatch.observer/filing/0001104659-22-114206.json
- Plain text: https://secwatch.observer/filing/0001104659-22-114206.txt

## Key facts
- Executive change
  Lisa von Moltke, M.D. was appointed as Director at Tvardi Therapeutics, Inc..
  - Action: appointed
  - Role: Director
  source text: On November 1, 2022, the Board of Directors (the “Board”) of Cara Therapeutics, Inc. (the “Company”) appointed Lisa von Moltke, M.D. to serve as a member of the Board
  evidence_url: https://www.sec.gov/Archives/edgar/data/1346830/000110465922114206/0001104659-22-114206-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.