---
schema_version: "secwatch.filing_event.v1"
accession: "0001104659-22-114437"
form_type: "8-K"
ticker: "CYRX"
cik: "0001124524"
company_name: "Cryoport, Inc."
filed_at: "2022-11-03T23:59:59+00:00"
generated_at: "2026-06-22T07:58:27.132115+00:00"
event_type: "earnings"
sentiment: "negative"
materiality_score: 0.75
calibrated_materiality_score: 0.75
confidence: "high"
source: SEC EDGAR
---

# Cryoport Q3 revenue up 7% to $60.5M, cuts FY 2022 guidance to $232-$238M on macro headwinds

## Summary
- Q3 revenue $60.5M (+7% YoY); net loss $7.3M ($0.15/share); adj. EBITDA $4.7M vs $6.0M YoY.
- Full-year 2022 revenue guidance cut to $232-$238M, citing FX, COVID China, supply chain, Ukraine war headwinds.
- Supported 643 global clinical trials (+61 YoY); entered apheresis partnership with Takeda's BioLife.
- Cash $530M; repurchased 1.34M shares for $33.3M at avg $24.84; $100M program authorized through 2025.
- Gross margin 43.7% (+222 bps YoY); operating costs rose 22% to $34.2M.

## SEC filing metadata
- accession: 0001104659-22-114437
- form_type: 8-K
- ticker: CYRX
- cik: 0001124524
- company_name: Cryoport, Inc.
- filed_at: 2022-11-03T23:59:59+00:00
- event_type: earnings
- sentiment: negative
- materiality_score: 0.75
- calibrated_materiality_score: 0.75
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1124524/000110465922114437/0001104659-22-114437-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1124524/000110465922114437/tm2229676d1_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001104659-22-114437
- JSON: https://secwatch.observer/filing/0001104659-22-114437.json
- Plain text: https://secwatch.observer/filing/0001104659-22-114437.txt

## Key facts
- Earnings Releases
  Cryoport, Inc. reported the third quarter ended September 30, 2022 results: revenue $60.5 million. Guidance lowered.
  - Period: the third quarter ended September 30, 2022
  - Revenue: $60.5 million
  - Guidance: lowered
  - Result: reported results
  source text: Cryoport Reports Results for the Third Quarter 2022 § Third quarter revenue of $60.5 million; nine months 2022 revenue reaches $176.9 million; Cryoport Systems’ revenue up 25% year-over-year
  evidence_url: https://www.sec.gov/Archives/edgar/data/1124524/000110465922114437/0001104659-22-114437-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.