secwatch.observer — SEC 8-K summary ====================================== Issuer: RHYTHM PHARMACEUTICALS, INC. (RYTM) CIK: 0001649904 Form: 8-K Filed at: 2022-11-03T23:59:59+00:00 Accession: 0001104659-22-114457 Event type: other_material Sentiment: negative Materiality: 0.72 Item codes: 1.02, 1.01 LLM model: deepseek-v4-flash:cloud@v2 Rhythm Pharmaceuticals terminates setmelanotide license with RareStone for cause over clinical trial breaches -------------------------------------------------------------------------------- - Terminated exclusive license for setmelanotide in Greater China (China, Hong Kong, Macao) effective Oct 28, 2022. - Termination for cause: RareStone materially breached obligations to fund and perform key clinical studies including EMANATE trial. - RareStone objects to termination and says formal response is forthcoming; potential dispute or litigation. - Agreement originally dated Dec 3, 2021 granted RareStone rights to develop and commercialize setmelanotide in Greater China. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1649904/000110465922114457/0001104659-22-114457-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1649904/000110465922114457/tm2229621d1_8k.htm HTML page: https://secwatch.observer/filing/0001104659-22-114457 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer