---
schema_version: "secwatch.filing_event.v1"
accession: "0001104659-22-117650"
form_type: "8-K"
ticker: "PMN"
cik: "0001374339"
company_name: "ProMIS Neurosciences Inc."
filed_at: "2022-11-14T23:59:59+00:00"
generated_at: "2026-06-21T19:44:24.569428+00:00"
event_type: "earnings"
sentiment: "negative"
materiality_score: 0.55
calibrated_materiality_score: 0.55
confidence: "high"
source: SEC EDGAR
---

# ProMIS Q3 net loss $6.0M vs $1.2M YoY; cash down to $4.0M; CEO change and $7.4M PIPE closed

## Summary
- Net loss of $6.0M for Q3 2022, up from $1.2M in Q3 2021; R&D expenses rose to $4.6M from $0.8M.
- Cash and equivalents $4.0M at Sep 30, 2022, down from $17.0M at Dec 31, 2021; Oct 2022 PIPE netted $6.4M.
- Gail Farfel appointed CEO effective Sep 19, 2022; co-founder Eugene Williams remains Chairman.
- IND submission for Alzheimer's candidate PMN310 progressing; first subject enrollment expected H1 2023.
- ALS candidate PMN267 and MSA candidate PMN442 advancing; vaccine program ongoing.

## SEC filing metadata
- accession: 0001104659-22-117650
- form_type: 8-K
- ticker: PMN
- cik: 0001374339
- company_name: ProMIS Neurosciences Inc.
- filed_at: 2022-11-14T23:59:59+00:00
- event_type: earnings
- sentiment: negative
- materiality_score: 0.55
- calibrated_materiality_score: 0.55
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1374339/000110465922117650/0001104659-22-117650-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1374339/000110465922117650/tm2224043d2_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001104659-22-117650
- JSON: https://secwatch.observer/filing/0001104659-22-117650.json
- Plain text: https://secwatch.observer/filing/0001104659-22-117650.txt

## Key facts
- Earnings Releases
  ProMIS Neurosciences Inc. reported the third quarter ended September 30, 2022 results: net income Net loss was $6.0 million.
  - Period: the third quarter ended September 30, 2022
  - Net income: Net loss was $6.0 million
  - Result: reported results
  source text: Net loss was $6.0 million for the third quarter ended September 30, 2022, compared to $1.2 million for the same period in 2021.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1374339/000110465922117650/0001104659-22-117650-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.