---
schema_version: "secwatch.filing_event.v1"
accession: "0001104659-23-024795"
form_type: "8-K"
ticker: "CYRX"
cik: "0001124524"
company_name: "Cryoport, Inc."
filed_at: "2023-02-23T23:59:59+00:00"
generated_at: "2026-06-19T01:28:45.981029+00:00"
event_type: "earnings"
sentiment: "neutral"
materiality_score: 0.7
calibrated_materiality_score: 0.7
confidence: "high"
source: SEC EDGAR
---

# Cryoport reports Q4 2022 revenue $60.4M, full-year record $237.3M; guides FY2023 revenue $270-290M

## Summary
- Full-year 2022 revenue $237.3M, up 7% YoY; commercial therapy revenue up 27% to $16.3M.
- Net loss attributable to common stockholders $45.3M ($0.93/share) vs $283.7M ($6.18/share) in 2021.
- Adjusted EBITDA $13.7M for 2022, down from $21.2M in 2021; Q4 adjusted EBITDA $0.7M.
- Cash and short-term investments $523.3M at year-end; repurchased 1.6M shares for $37.9M in 2022.
- FY2023 revenue guidance $270-290M (18% growth at midpoint); supporting 654 clinical trials and 10 commercial therapies.

## SEC filing metadata
- accession: 0001104659-23-024795
- form_type: 8-K
- ticker: CYRX
- cik: 0001124524
- company_name: Cryoport, Inc.
- filed_at: 2023-02-23T23:59:59+00:00
- event_type: earnings
- sentiment: neutral
- materiality_score: 0.7
- calibrated_materiality_score: 0.7
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1124524/000110465923024795/0001104659-23-024795-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1124524/000110465923024795/tm237715d1_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001104659-23-024795
- JSON: https://secwatch.observer/filing/0001104659-23-024795.json
- Plain text: https://secwatch.observer/filing/0001104659-23-024795.txt

## Key facts
- Earnings Releases
  Cryoport, Inc. reported the fiscal year ended December 31, 2022 results: revenue $237.3 million. Guidance initiated.
  - Period: the fiscal year ended December 31, 2022
  - Revenue: $237.3 million
  - Guidance: initiated
  - Result: reported results
  source text: Cryoport delivered a solid finish to 2022 with total revenue of $237.3 million
  evidence_url: https://www.sec.gov/Archives/edgar/data/1124524/000110465923024795/0001104659-23-024795-index.htm
- Earnings Releases
  Cryoport, Inc. reported the three months ended December 31, 2022 results: revenue $60.4 million. Guidance initiated.
  - Period: the three months ended December 31, 2022
  - Revenue: $60.4 million
  - Guidance: initiated
  - Result: reported results
  source text: Total revenue for the fourth quarter of 2022 was $60.4 million compared to $56.4 million for the fourth quarter of 2021, a year-over-year increase of 7%
  evidence_url: https://www.sec.gov/Archives/edgar/data/1124524/000110465923024795/0001104659-23-024795-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.