---
schema_version: "secwatch.filing_event.v1"
accession: "0001104659-23-039153"
form_type: "8-K"
ticker: "HYPD"
cik: "0001682639"
company_name: "HYPERION DEFI, INC."
filed_at: "2023-03-30T23:59:59+00:00"
generated_at: "2026-06-17T09:19:56.377961+00:00"
event_type: "earnings"
sentiment: "neutral"
materiality_score: 0.65
calibrated_materiality_score: 0.65
confidence: "high"
source: SEC EDGAR
---

# Eyenovia reports FY2022 net loss $28.0M; Mydcombi PDUFA date May 8, 2023

## Summary
- Net loss $28.0M ($0.83/share) for FY2022 vs $12.8M loss in FY2021; Q4 loss $6.1M.
- Cash and equivalents $22.9M at Dec 31, 2022, down from $27.3M at Dec 31, 2021.
- FDA accepted Mydcombi NDA; PDUFA action target date May 8, 2023.
- Positive Phase 3 results for Microline (presbyopia); FDA feedback outlines clear path forward.
- Co-development agreement with Formosa Pharmaceuticals to combine Optejet with APNT nanoparticle platform.

## SEC filing metadata
- accession: 0001104659-23-039153
- form_type: 8-K
- ticker: HYPD
- cik: 0001682639
- company_name: HYPERION DEFI, INC.
- filed_at: 2023-03-30T23:59:59+00:00
- event_type: earnings
- sentiment: neutral
- materiality_score: 0.65
- calibrated_materiality_score: 0.65
- confidence: high
- sec_items: 2.02, 8.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1682639/000110465923039153/0001104659-23-039153-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1682639/000110465923039153/tm2311016d1_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001104659-23-039153
- JSON: https://secwatch.observer/filing/0001104659-23-039153.json
- Plain text: https://secwatch.observer/filing/0001104659-23-039153.txt

## Key facts
- Earnings Releases
  HYPERION DEFI, INC. reported fourth quarter ended December 31, 2022 results: net income net loss was approximately $[6.1] million, or $[0.17] per share, EPS $[0.17] per share.
  - Period: fourth quarter ended December 31, 2022
  - Net income: net loss was approximately $[6.1] million, or $[0.17] per share
  - EPS: $[0.17] per share
  - Result: reported results
  source text: For the fourth quarter of 2022, net loss was approximately $[6.1] million, or $[0.17] per share compared to a net income of approximately $3.0 million, or $0.11 per share, for the fourth quarter of 2021.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1682639/000110465923039153/0001104659-23-039153-index.htm
- Earnings Releases
  HYPERION DEFI, INC. reported fiscal year ended December 31, 2022 results: net income net loss was approximately $[28.0] million, or $[0.83] per share on approximately 33.6 million weighted average shares o, EPS $[0.83] per share.
  - Period: fiscal year ended December 31, 2022
  - Net income: net loss was approximately $[28.0] million, or $[0.83] per share on approximately 33.6 million weighted average shares o
  - EPS: $[0.83] per share
  - Result: reported results
  source text: For the full-year 2022, net loss was approximately $[28.0] million, or $[0.83] per share on approximately 33.6 million weighted average shares outstanding, and this compares to a net loss of approximately $[12.8] million, or $[0.49] per share, for the full year 2021 on approximately 26.3 million weighted average shares outstanding.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1682639/000110465923039153/0001104659-23-039153-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.