{"schema_version":"secwatch.filing_event.v1","accession":"0001104659-23-039267","form_type":"8-K","ticker":"GPCR","cik":"0001888886","company_name":"Structure Therapeutics Inc.","filed_at":"2023-03-30T23:59:59+00:00","discovered_at":"2026-05-14T18:03:47.345597+00:00","generated_at":"2026-06-17T09:47:14.523241+00:00","sec_items":["2.02","9.01"],"event_type":"other_material","sentiment":"neutral","materiality_score":0.6,"calibrated_materiality_score":0.6,"confidence":"high","headline":"Structure Therapeutics reports Q4 2022 net loss $11.9M; GSBR-1290 Phase 1b dosing complete","bullets":["Completed dosing of GSBR-1290 Phase 1b in healthy overweight volunteers; topline data from Phase 1b and Phase 2a expected 2H 2023.","Completed $185.3M upsized IPO in Feb 2023; net proceeds ~$166.7M; cash position $249.4M as of Feb 28, 2023.","Cash, cash equivalents and marketable securities $90.8M at Dec 31, 2022; expects to fund operations through end of 2025.","Net loss $11.9M Q4 2022 vs $13.4M Q4 2021; full year net loss $51.3M vs $38.0M in 2021.","R&D expenses $8.4M Q4 2022, $36.2M full year; G&A $4.6M Q4, $16.4M full year."],"urls":{"canonical":"https://secwatch.observer/filing/0001104659-23-039267","json":"https://secwatch.observer/filing/0001104659-23-039267.json","markdown":"https://secwatch.observer/filing/0001104659-23-039267.md","text":"https://secwatch.observer/filing/0001104659-23-039267.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1888886/000110465923039267/0001104659-23-039267-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1888886/000110465923039267/tm2310702d1_8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-17T09:47:14.523241+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}