secwatch.observer — SEC 8-K summary ====================================== Issuer: Transcode Therapeutics, Inc. (RNAZ) CIK: 0001829635 Form: 8-K Filed at: 2023-03-31T23:59:59+00:00 Accession: 0001104659-23-040152 Event type: earnings Sentiment: negative Materiality: 0.85 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 TransCode Therapeutics reports 2022 operating loss of $17.9M; cash runway into Q2 2023 -------------------------------------------------------------------------------- - Cash at Dec 31, 2022: $5.0M, down from $20.8M at Dec 31, 2021. - Operating loss of $17.9M in 2022 vs $6.8M in 2021; R&D expense $10.5M (up from $2.8M). - Cash of $5.0M plus $1.3M from Feb 2023 offering and $871k SBIR expected to fund into but not through Q2 2023. - FDA authorized Phase 0 FIH trial for lead candidate TTX-MC138 in advanced solid tumors. - Strategic alliance with MD Anderson and Orphan Drug Designation for TTX-siPDL1 in pancreatic cancer. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1829635/000110465923040152/0001104659-23-040152-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1829635/000110465923040152/tm2310837d1_8k.htm HTML page: https://secwatch.observer/filing/0001104659-23-040152 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer