secwatch.observer — SEC 8-K summary ====================================== Issuer: Annovis Bio, Inc. (ANVS) CIK: 0001477845 Form: 8-K Filed at: 2023-04-03T23:59:59+00:00 Accession: 0001104659-23-040537 Event type: earnings Sentiment: neutral Materiality: 0.70 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Annovis Bio reports Q4 2022 net loss of $7.7M; advances buntanetap trials ------------------------------------------------------------------------- - Net loss Q4 2022 of $7.7M vs $5.9M in Q4 2021; full-year net loss $25.3M vs $14.5M. - Cash and equivalents $28.4M as of Dec 31, 2022; R&D spend $6.2M in Q4, up 114% YoY. - FDA authorized Phase 2/3 Alzheimer's trial; EU sites approved for Phase 3 Parkinson's trial. - Interim analysis for Phase 3 PD trial based on 132 patients; company proceeds as planned. - Appointed VP Process Chemistry and VP Toxicology; filed patent for neuropsychiatric uses. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1477845/000110465923040537/0001104659-23-040537-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1477845/000110465923040537/tm2311180d1_8k.htm HTML page: https://secwatch.observer/filing/0001104659-23-040537 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer