regulatory
confidence high
sentiment positive
materiality 0.75
ProMIS Neurosciences submits IND to FDA for Alzheimer's antibody PMN310
ProMIS Neurosciences Inc.
- IND filed for PMN310, a monoclonal antibody targeting toxic amyloid-beta oligomers in Alzheimer's disease.
- PMN310 designed for high selectivity to toxic oligomers, potentially reducing ARIA risk vs other antibodies.
- Company expects to become a clinical-stage company pending FDA clearance of the IND.
- Preclinical data showed strong ex vivo target engagement and favorable in vitro comparison to other Aβ antibodies.