secwatch.observer — SEC 8-K summary ====================================== Issuer: CYPHERPUNK TECHNOLOGIES INC. (CYPH) CIK: 0001509745 Form: 8-K Filed at: 2023-04-12T23:59:59+00:00 Accession: 0001104659-23-044293 Event type: other_material Sentiment: neutral Materiality: 0.50 Item codes: 8.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Leap Therapeutics completes Part A enrollment (33 pts) in Phase 2 DeFianCe study of DKN-01 for colorectal cancer -------------------------------------------------------------------------------- - Part A enrolled 33 patients with advanced colorectal cancer; study is randomized, open-label, multicenter. - Part B is planned as a 130-patient randomized controlled trial; primary endpoint is progression-free survival. - Initial data from the study expected in mid-2023. - Secondary endpoints include overall response rate, duration of response, and overall survival. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1509745/000110465923044293/0001104659-23-044293-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1509745/000110465923044293/tm2312449d1_8k.htm HTML page: https://secwatch.observer/filing/0001104659-23-044293 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer