other material
confidence high
sentiment negative
materiality 0.75
INTERCEPT PHARMACEUTICALS, INC.: restructuring charge — Intercept cuts ~1/3 workforce, ends NASH investment, targets 2024 profitability
INTERCEPT PHARMACEUTICALS, INC.
- Workforce reduction of approximately one third; restructuring costs of ~$16M (mostly cash severance).
- Discontinues all NASH-related investment; closes REGENERATE study by end of 2023.
- Lowers 2023 non-GAAP adjusted opex guidance to $350-370M; targets ~$140M annual opex savings.
- Reiterates 2023 Ocaliva net sales guidance of $310-340M; aims for profitability in 2024.
- Prioritizes R&D on fixed-dose OCA-bezafibrate combination for PBC; Phase 2 interim analyses expected in 2023.