secwatch.observer — SEC 8-K summary ====================================== Issuer: Quoin Pharmaceuticals, Ltd. (QNRX) CIK: 0001671502 Form: 8-K Filed at: 2023-11-09T23:59:59+00:00 Accession: 0001104659-23-116370 Event type: other_material Sentiment: positive Materiality: 0.85 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Quoin reports positive Phase 2 data for QRX003 in Netherton Syndrome; cash $14M ------------------------------------------------------------------------------- - Five of six evaluable subjects showed negligible/absent pruritus after QRX003 treatment in open-label study. - All six subjects improved in Investigator skin scoring; favorable patient global assessment across metrics. - No safety concerns in either ongoing study; protocol amendments planned: eliminate lower 2% dose, twice-daily dosing. - Cash, equivalents and marketable securities $14.0M as of Sept 30, 2023; runway expected through end of 2024. - Net loss $2.1M for Q3 2023 vs $2.3M for Q3 2022; nine-month net loss $7.2M flat year-over-year. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1671502/000110465923116370/0001104659-23-116370-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1671502/000110465923116370/tm2330370d1_8k.htm HTML page: https://secwatch.observer/filing/0001104659-23-116370 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer