{"schema_version":"secwatch.filing_event.v1","accession":"0001104659-24-001799","form_type":"8-K","ticker":"BRNS","cik":"0001828185","company_name":"Barinthus Biotherapeutics plc.","filed_at":"2024-01-05T23:59:59+00:00","discovered_at":"2026-05-14T18:03:25.782099+00:00","generated_at":"2026-06-07T03:21:30.716201+00:00","sec_items":["2.02","7.01","9.01"],"event_type":"other_material","sentiment":"neutral","materiality_score":0.55,"calibrated_materiality_score":0.55,"confidence":"high","headline":"Barinthus Bio reports $142M cash, extends runway to Q4 2025, details 2024 milestones","bullets":["Preliminary cash and equivalents: $142M as of Dec 31, 2023; ~38.6M ordinary shares outstanding.","Cash runway extended from Q2 to Q4 2025 by deferring VTP-1100 IND in HPV cancer and phasing manufacturing.","H1 2024: initiate Phase 1 trial of VTP-1000 in Celiac Disease; final Phase 1b/2 VTP-200 (HPV) data.","H1 2024: interim data from HBV003 (Phase 2b VTP-300 dosing) and AB-729-202 (VTP-300 + imdusiran) trials.","H2 2024: interim data from third arm of AB-729-202 adding nivolumab to VTP-300 and imdusiran."],"urls":{"canonical":"https://secwatch.observer/filing/0001104659-24-001799","json":"https://secwatch.observer/filing/0001104659-24-001799.json","markdown":"https://secwatch.observer/filing/0001104659-24-001799.md","text":"https://secwatch.observer/filing/0001104659-24-001799.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1828185/000110465924001799/0001104659-24-001799-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1828185/000110465924001799/tm242118d1_8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-07T03:21:30.716201+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}