other material
confidence high
sentiment positive
materiality 0.90
Cellectar announces positive pivotal trial data for iopofosine I 131 in WM
Cellectar Biosciences, Inc.
- CLOVER-WaM study met primary endpoint with 61% major response rate (p<0.0001), exceeding 20% statistical hurdle.
- Overall response rate of 75.6% and 100% disease control in heavily pretreated, BTKi-refractory WM patients.
- Median duration of response not yet reached at median 8-month follow-up; 76% remain progression-free.
- No treatment-related discontinuations or deaths; Grade 3+ cytopenias manageable with no bleeding or febrile neutropenia beyond 2%.