---
schema_version: "secwatch.filing_event.v1"
accession: "0001104659-24-035239"
form_type: "8-K"
ticker: "CYPH"
cik: "0001509745"
company_name: "CYPHERPUNK TECHNOLOGIES INC."
filed_at: "2024-03-18T23:59:59+00:00"
generated_at: "2026-06-04T15:04:22.254029+00:00"
event_type: "earnings"
sentiment: "neutral"
materiality_score: 0.6
calibrated_materiality_score: 0.6
confidence: "high"
source: SEC EDGAR
---

# Leap Therapeutics reports FY2023 net loss $81.4M; cash $70.6M; DKN-01 data positive

## Summary
- Net loss $81.4M in FY2023 vs $54.6M in FY2022; R&D expenses $73.2M.
- Cash and equivalents $70.6M at Dec 31, 2023; research incentive receivables $0.8M.
- DeFianCe Part A (CRC): 30% ORR, 93% DCR; median PFS 6.3 months in 2L MSS CRC.
- Completed enrollment (170 pts) in DisTinGuish Part C for gastric/GEJ cancer; data expected mid-2024.
- Randomized Part B of DeFianCe (130 pts) enrolling; 80 enrolled as of Mar 15, 2024.

## SEC filing metadata
- accession: 0001104659-24-035239
- form_type: 8-K
- ticker: CYPH
- cik: 0001509745
- company_name: CYPHERPUNK TECHNOLOGIES INC.
- filed_at: 2024-03-18T23:59:59+00:00
- event_type: earnings
- sentiment: neutral
- materiality_score: 0.6
- calibrated_materiality_score: 0.6
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1509745/000110465924035239/0001104659-24-035239-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1509745/000110465924035239/tm248524d1_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001104659-24-035239
- JSON: https://secwatch.observer/filing/0001104659-24-035239.json
- Plain text: https://secwatch.observer/filing/0001104659-24-035239.txt

## Key facts
- Earnings Releases
  CYPHERPUNK TECHNOLOGIES INC. reported the year ended December 31, 2023 results: net income $81.4 million.
  - Period: the year ended December 31, 2023
  - Net income: $81.4 million
  - Result: reported results
  source text: Net Loss was $81.4 million for the year ended December 31, 2023,
  evidence_url: https://www.sec.gov/Archives/edgar/data/1509745/000110465924035239/0001104659-24-035239-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.