{"schema_version":"secwatch.filing_event.v1","accession":"0001104659-24-037855","form_type":"8-K","ticker":"TVRD","cik":"0001346830","company_name":"Tvardi Therapeutics, Inc.","filed_at":"2024-03-22T23:59:59+00:00","discovered_at":"2026-05-14T18:03:23.884856+00:00","generated_at":"2026-06-04T08:59:32.212081+00:00","sec_items":["5.02"],"event_type":"leadership","sentiment":"neutral","materiality_score":0.55,"calibrated_materiality_score":0.55,"confidence":"high","headline":"Cara Therapeutics CMO Joana Goncalves resigns effective April 16, 2024","bullets":["Dr. Joana Goncalves notified Company of resignation on March 19, 2024.","Departure is to pursue another opportunity and not related to any disagreement.","She will remain CMO through April 16, 2024, assisting in transition.","Duties will be assumed by other senior management team members."],"urls":{"canonical":"https://secwatch.observer/filing/0001104659-24-037855","json":"https://secwatch.observer/filing/0001104659-24-037855.json","markdown":"https://secwatch.observer/filing/0001104659-24-037855.md","text":"https://secwatch.observer/filing/0001104659-24-037855.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1346830/000110465924037855/0001104659-24-037855-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1346830/000110465924037855/tm249486d1_8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-04T08:59:32.212081+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[{"claim_id":"370bf05406","claim":"Joana Goncalves resigned as Chief Medical Officer at Tvardi Therapeutics, Inc..","evidence_excerpt":"On March 19, 2024, Dr. Joana Goncalves, the Chief Medical Officer of Cara Therapeutics, Inc. (the “Company”), informed the Company of her intention to resign from her role effective April 16, 2024, to pursue another opportunity.","evidence_source":"SEC 8-K Item 5.02","evidence_url":"https://www.sec.gov/Archives/edgar/data/1346830/000110465924037855/0001104659-24-037855-index.htm","confidence":0.95,"family_label":"Executive change","details":[{"label":"Action","value":"resigned"},{"label":"Role","value":"Chief Medical Officer"}],"fact_type":"executive_change"}],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}