other material
confidence high
sentiment positive
materiality 0.70
Marker Therapeutics: MT-601 shows durable CR in lymphoma patient 9 months post-CAR T failure; 3/3 objective responses
Marker Therapeutics, Inc.
- First APOLLO participant with DLBCL who relapsed after CAR T remains in complete response 9 months after MT-601 treatment.
- Second participant with transformed follicular NHL achieved CR at 8 weeks and remains in CR at 3 months.
- Third participant with DLBCL (CAR T-ineligible) achieved partial response at 8 weeks with lesion shrinkage.
- All three patients tolerated treatment well; no cytokine release syndrome or neurotoxicity reported.
- Data presented at 11th Global Summit on Hematologic Malignancies on April 6, 2024 by City of Hope PI Dr. Shouse.