other material
confidence high
sentiment positive
materiality 0.65
Century Therapeutics updates pipeline; CNTY-101 achieves 40% CRR at higher doses; SLE trial starts Q3 2024
Century Therapeutics, Inc.
- CNTY-101 ELiPSE-1 Phase 1 data: 30% CRR, 40% ORR overall; 40% CRR, 60% ORR at highest dose levels in Schedule A.
- CNTY-101 shows favorable safety: no GvHD, low-grade CRS/ICANS, manageable outpatient administration.
- Phase 1 CALiPSO-1 trial for SLE (systemic lupus erythematosus) initiated early Q3 2024; initial data expected by YE 2024.
- Cash of $249.9M at 1Q24 end provides runway into 2026.
- Pursuing additional autoimmune regulatory submissions for CNTY-101 in 2H 2024.