{"schema_version":"secwatch.filing_event.v1","accession":"0001104659-24-087275","form_type":"8-K","ticker":"GPCR","cik":"0001888886","company_name":"Structure Therapeutics Inc.","filed_at":"2024-08-08T23:59:59+00:00","discovered_at":"2026-05-14T18:03:15.111647+00:00","generated_at":"2026-05-31T11:19:02.981208+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"neutral","materiality_score":0.7,"calibrated_materiality_score":0.7,"confidence":"high","headline":"Structure Therapeutics Q2 net loss $26M; cash $927M; GSBR-1290 Phase 2b on track Q4 2024","bullets":["Q2 2024 net loss $26.0M vs $23.3M in Q2 2023; R&D expenses $22.1M, G&A $11.3M.","Cash, equivalents and short-term investments $927.1M expected to fund operations through at least 2027.","GSBR-1290 Phase 2b obesity study on track to initiate in Q4 2024; Phase 2a showed 6.2% placebo-adjusted weight loss at 12 weeks.","Amylin receptor agonist development candidate expected to be selected in Q4 2024; GIPR candidate expected H1 2025.","Phase 1 trial of LTSE-2578 (LPA1R antagonist for IPF) initiated in June 2024."],"urls":{"canonical":"https://secwatch.observer/filing/0001104659-24-087275","json":"https://secwatch.observer/filing/0001104659-24-087275.json","markdown":"https://secwatch.observer/filing/0001104659-24-087275.md","text":"https://secwatch.observer/filing/0001104659-24-087275.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1888886/000110465924087275/0001104659-24-087275-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1888886/000110465924087275/tm2421118d1_8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-31T11:19:02.981208+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}