---
schema_version: "secwatch.filing_event.v1"
accession: "0001104659-24-104002"
form_type: "8-K"
ticker: "ANVS"
cik: "0001477845"
company_name: "Annovis Bio, Inc."
filed_at: "2024-09-30T23:59:59+00:00"
generated_at: "2026-05-31T00:42:53.899836+00:00"
event_type: "other_material"
sentiment: "positive"
materiality_score: 0.5
calibrated_materiality_score: 0.5
confidence: "medium"
source: SEC EDGAR
---

# Annovis files three new patents for Buntanetap combinations with Trulicity and Viagra

## Summary
- Patents cover Buntanetap + Trulicity (GLP-1), Buntanetap + Viagra (PDE5i), and triple combo.
- Preclinical synergy data showed cognition in AD mouse models improved beyond healthy controls.
- Combinations positioned for Phase 3 trials; Buntanetap completed Phase 3; Trulicity and Viagra are FDA-approved.
- CEO: combination could restore and improve cognition, offering new hope in dementia fight.
- Annovis expands IP portfolio for neurodegenerative disorders with these filings.

## SEC filing metadata
- accession: 0001104659-24-104002
- form_type: 8-K
- ticker: ANVS
- cik: 0001477845
- company_name: Annovis Bio, Inc.
- filed_at: 2024-09-30T23:59:59+00:00
- event_type: other_material
- sentiment: positive
- materiality_score: 0.5
- calibrated_materiality_score: 0.5
- confidence: medium
- sec_items: 7.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1477845/000110465924104002/0001104659-24-104002-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1477845/000110465924104002/tm2425199d1_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001104659-24-104002
- JSON: https://secwatch.observer/filing/0001104659-24-104002.json
- Plain text: https://secwatch.observer/filing/0001104659-24-104002.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.