secwatch.observer — SEC 8-K summary ====================================== Issuer: Quoin Pharmaceuticals, Ltd. (QNRX) CIK: 0001671502 Form: 8-K Filed at: 2025-01-06T23:59:59+00:00 Accession: 0001104659-25-001350 Event type: other_material Sentiment: positive Materiality: 0.75 Item codes: 8.01 LLM model: deepseek-v4-flash:cloud@v2 Quoin reports Netherton Syndrome patient achieves near-clear skin after 12 weeks of QRX003 twice-daily -------------------------------------------------------------------------------- - M-IASI score improved from 18 to 3; WINRS from 7 to 2; IGA from Moderate to Almost Clear after 12 weeks. - Patient satisfaction scores further improved from 6-week to 12-week mark; no safety concerns observed. - Data follows positive interim results announced Dec 2024; first subject completed full 12-week twice-daily dosing with QRX003. - Quoin is developing QRX003 for Netherton Syndrome, a rare genetic skin disorder with no approved therapies. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1671502/000110465925001350/0001104659-25-001350-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1671502/000110465925001350/tm252105d1_8k.htm HTML page: https://secwatch.observer/filing/0001104659-25-001350 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer