other material
confidence high
sentiment neutral
materiality 0.55
Carisma updates pipeline: CT-1119 Phase 1 start H1 2025, liver fibrosis IND in 2026
Carisma Therapeutics Inc.
- CT-1119 (mesothelin-targeted CAR-Monocyte) Phase 1 trial with tislelizumab in solid tumors expected to start H1 2025.
- Phase 1 trial to enroll up to 12 patients in China; initial safety/efficacy data anticipated Q4 2025.
- Liver fibrosis program: preclinical in 2025 to enable regulatory submission in 2026, followed by Phase 1 in 2026.
- Corporate presentation updated on company website with these pipeline milestones.