{"schema_version":"secwatch.filing_event.v1","accession":"0001104659-25-004132","form_type":"8-K","ticker":"QNRX","cik":"0001671502","company_name":"Quoin Pharmaceuticals, Ltd.","filed_at":"2025-01-16T23:59:59+00:00","discovered_at":"2026-05-14T18:03:04.384912+00:00","generated_at":"2026-05-28T00:08:13.447067+00:00","sec_items":["8.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.65,"calibrated_materiality_score":0.65,"confidence":"high","headline":"Quoin reports positive QRX003 data in Netherton Syndrome: IGA improves from severe to mild after 6 weeks","bullets":["IGA score improved from 'severe' at baseline to 'mild' after six weeks of twice-daily QRX003 dosing.","After 12 days of dosing, IGA was 'mild-moderate'; full 6-week data confirms continued improvement.","Subject transitioned from 20% BSA treatment to whole-body application based on positive results.","No adverse events or safety concerns reported for this subject, consistent with prior studies.","Data from ongoing 12-week Investigator Pediatric Study supports QRX003's potential in Netherton Syndrome."],"urls":{"canonical":"https://secwatch.observer/filing/0001104659-25-004132","json":"https://secwatch.observer/filing/0001104659-25-004132.json","markdown":"https://secwatch.observer/filing/0001104659-25-004132.md","text":"https://secwatch.observer/filing/0001104659-25-004132.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1671502/000110465925004132/0001104659-25-004132-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1671502/000110465925004132/tm253523d1_8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-28T00:08:13.447067+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}